Name: Cytokines: From Basic Mechanisms of Cellular Control to new Therapeutics (Perspectives Cshl) (en Inglés)
Price: 2730.00 UYU
Availability: InStock
Author: Warren J. (Edt) Schreiber Robert (Edt)/ Leonard
ISBN: 9781621821250

portada Cytokines: From Basic Mechanisms of Cellular Control to new Therapeutics (Perspectives Cshl) (en Inglés)

Cytokines: From Basic Mechanisms of Cellular Control to new Therapeutics (Perspectives Cshl) (en Inglés)

Formato

Libro Físico

Editorial

Cold Spring Harbor Laboratory Press

Autor

Warren J. (Edt) Schreiber Robert (Edt)/ Leonard

Categoría

Libros de Textos

Año

2018

Idioma

Inglés

N° páginas

350

Encuadernación

Tapa Dura

ISBN13

9781621821250

N° edición

Cytokines: From Basic Mechanisms of Cellular Control to new Therapeutics (Perspectives Cshl) (en Inglés)

Warren J. (Edt) Schreiber Robert (Edt)/ Leonard (Autor) · Cold Spring Harbor Laboratory Press · Tapa Dura

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Reseña del libro "Cytokines: From Basic Mechanisms of Cellular Control to new Therapeutics (Perspectives Cshl) (en Inglés)"

Cytokines (e.g., interleukins and interferons) are small signaling proteins that are essential for communication between cells. They are important regulators of the immune system, helping to control lymphocyte development and function, orchestrate inflammation, and defeat microbial and viral invaders. But they also play important roles in the nervous system, embryonic development, and diseases such as cancer. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers the spectrum of cytokines that are produced and their roles in normal physiology and disease. The contributors examine the numerous cytokines and their cognate receptors, the downstream signaling mechanisms (e.g., JAK-STAT pathways) that mediate the effects of cytokines on cells, and the regulators that keep them in check (e.g., long noncoding RNAs and the SOCS and IRF protein families). These molecular interactions are discussed in the context of their physiological effects; the roles of cytokines in the development and activities of the immune system are emphasized.The authors also explore how the actions of cytokines may be modulated for treating patients with autoimmune disorders, immunodeficiency, infections, allergies, and cancer. Thus, this volume is an indispensable reference not only for cell biologists and immunologists but for all who are interested in targeting cytokine signaling for therapeutic purposes.